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Cancer Chemotherapy, Immunotherapy, and Biotherapy
  • Language: en
  • Pages: 1541

Cancer Chemotherapy, Immunotherapy, and Biotherapy

Focusing on individual patient needs, Cancer Chemotherapy, Immunotherapy and Biotherapy: Principles and Practice, Seventh Edition, provides thorough, comprehensive information from Drs. Bruce A. Chabner, Dan L. Longo, and an authoritative team of clinicians and scientists working at renowned cancer centers across the globe. It covers fundamental information about mechanism of action, pharmacokinetics, clinical toxicity, and drug interactions, all essential to the safe and effective use of the drug.

Visible Light-Driven Organic Synthesis
  • Language: en
  • Pages: 408

Visible Light-Driven Organic Synthesis

  • Type: Book
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  • Published: 2024-08-12
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  • Publisher: Elsevier

Visible Light-Driven Organic Synthesis covers the recent cutting-edge investigations in the field of visible light– driven organic synthesis in a single comprehensive volume. It provides information on rigorously selected reaction schemes and covers new reactions and new methods under visible light photocatalysis. It enlists more than 100 important synthetic strategies/methodologies with particular emphasis on useful reactions for organic synthesis under the mild reaction conditions reported in recent times involving carbon–carbon (C–C) and carbon–heteroatom bond–forming reactions, resulting in a wide spectrum of chemical compounds, providing an outstanding source of information co...

Target Discovery and Validation
  • Language: en
  • Pages: 396

Target Discovery and Validation

The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Thro...

Inducing Targeted Protein Degradation
  • Language: en
  • Pages: 389

Inducing Targeted Protein Degradation

Enables drug developers in academia and industry to expand the range of accessible drug targets through induced protein degradation Since the introduction of the PROTAC technology in 2015, targeted protein degradation has greatly increased the range of druggable protein targets, enabling pharma companies to develop completely novel therapeutics. Inducing Targeted Protein Degradation is a timely guide to navigating the complexities of the subject and understanding its practical application, with an eye on expanding the range of druggable targets. In Inducing Targeted Protein Degradation, readers will find the most recent information on: Cellular mechanisms of targeted protein degradation and ...

Protein Homeostasis in Drug Discovery
  • Language: en
  • Pages: 564

Protein Homeostasis in Drug Discovery

Protein Homeostasis in Drug Discovery Comprehensive resource on all aspects of protein homeostasis, covering both historical perspectives and emerging technologies that are revolutionizing the field Protein Homeostasis in Drug Discovery highlights drug discovery and development efforts targeting protein homeostasis and considers the emerging appreciation that a protein’s activity may not be the only factor to consider when developing therapeutic agents. The chapters cover various aspects of protein homeostasis such as cellular localization, abundance, interactions, and more. Moreover, the text contains up-to-date information regarding targeted protein degradation, an emerging drug discover...

Lions 3231A1 District Directory
  • Language: en
  • Pages: 295

Lions 3231A1 District Directory

Lions District Directory for District 3231A1 is published for the First Time, after its formation during the centennial year, by its District Governor MJF Lion Pradip M Parekh. The Print edition gives entire details of all its Clubs, Club Members, Office Bearers, Lion Leaders like ZC, RC, Core Cabinet, DG Team etc. This Digital Edition is published to enable portability of information through Smart Mobile Phones and eReaders, Lions Carry.

Cancer Drug Discovery
  • Language: en
  • Pages: 286

Cancer Drug Discovery

  • Type: Book
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  • Published: 2016-11-14
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  • Publisher: Springer

The reader will discover a comprehensive and multifaceted overview of the history of the development of anticancer drugs deeply influenced by the cell concept of cancer and future directions for the development of new anticancer drugs. First, this book documents the scientific progress in biological science over the last 70 years and the influence this progress had in cancer research. Summaries and charts of important discoveries complete this overview. Furthermore, this book outlines the process of anticancer drug development with a focus on the characteristic drug groups of each era, related to advancements of chemistry and biological sciences. This book also provides brief mechanism of action of drugs, illustrated by comprehensive timelines and conceptual cartoons. This book finally sums up the limitations of the current anticancer drug development and seeks new directions for anticancer drug discovery, considering under the systemic view of cancer.

Precision Cancer Therapies, Volume 2: Immunologic Approaches for the Treatment of Lymphoid Malignancies
  • Language: en
  • Pages: 501

Precision Cancer Therapies, Volume 2: Immunologic Approaches for the Treatment of Lymphoid Malignancies

Presents timely and authoritative information on the development of precision cancer therapies as applied to hematologic malignancies The Precision Cancer Therapies series focuses on how to understand and translate fundamental basic science into information that can be directly applied to patients to advance care. Each volume of the series integrates the relevant biological concepts and principles necessary for translating this science to practitioners of this science. Precision Cancer Therapies, Volume Two, focuses on sophisticated immunotherapies targeting cancers affecting the blood, bone marrow, and lymph nodes. Edited and authored by the foremost authorities in the field, this comprehen...